Ohio State’s first Big Ten road test brings a top-15 matchup, College GameDay and a return to Kinnick Stadium for the first time since 2017. Can Julian Sayin and Jeremiah Smith solve the nation’s No. 1 scoring defense—and can the Buckeyes fix the run-defense concerns Iowa is built to test? Our full Buckeye50 preview includes team breakdowns, injury updates, player spotlights, three keys, Jeremiah Smith’s record watch and a final score prediction.